Bioinformatics Practice Test 8

1. Which of the following is incorrect regarding Eponine?

The regulatory sites include the TATA box, the CCAAT box, and CpG islands

It is a web-based program that predicts transcription start sites

It is based on a series of pre-constructed PSSMs of several regulatory sites

It is a web-based program that particularly predicts tranpososons and retropososons

2. Which of the following is incorrect regarding BPROM?

It is a web-based program for prediction of bacterial promoters

The linear discriminant function is combined with signal and content information

It is a web-based program only for prediction of eukarotic promoters

It uses a linear discriminant function

3. The upstream sequence where the σ protein binds constitutes the promoter sequence.

False

True

4. In case of protein-protein docking, the level of success is dependent on the system under study.

False

True

5. Once an operon structure is known ______ for the presence of a promoter and regulatory elements _____ in the operon do not possess such DNA elements.

only first ten genes are predicted, whereas next few genes

only the first hundred genes are predicted, whereas next few genes

only the first gene is predicted, whereas other genes

only first two genes are predicted, whereas next few genes

6. TwinScan is also a similarity-based gene-finding Server and it is similar to GenomeScan in that it uses GenScan to predict all possible exons from the genomic sequence.

True

False

7. In BPROM, once the operons are assigned, the program is able to predict putative promoter sequences.

True

False

8. Which of the following is untrue about FGENES?

It does not make a use of HMMs

It stands for FindGenes

It is a web-based program that uses LDA

It is used to determine whether a signal is an exon

9. In Multiple conformation rigid-body method, a ligand is assumed to be able to adopt a number (N) of different _______ that are computed _____ the ligand being docked into the receptor.

low-energy conformations, prior to

high-energy conformations, prior to

high-energy conformations, after

low-energy conformations, after

10. In Grid representation, the lowest score represents the best surface complementarity for a given translational scan.

True

False