Bioinformatics Mock Test 5

10%

Question 1 of 10

1. ______ molecules can simply be identified based on their sequence similarity with already-known sequences.

Larger, highly conserved

smaller, highly conserved

Larger, less conserved

shorter, highly conserved

Question 1 of 10

Question 2 of 10

2. Genetic markers are ______ portions of a _______ whose inheritance patterns can be followed.

identifiable, genes

unidentifiable, genes

unidentifiable, chromosome

identifiable, chromosome

Question 2 of 10

Question 3 of 10

3. The shotgun approach does not require knowledge of physical mapping of the clone fragments, but rather a robust computer assembly program to join the pieces of random fragments into a single, whole-genome sequence.

True

False

Question 3 of 10

Question 4 of 10

4. Nussinov and Jacobson (1980) were the first to design a precise and efficient algorithm for predicting secondary structure.

False

True

Question 4 of 10

Question 5 of 10

5. The pre-alignment independent programs fare __________ for predicting long sequences.

much worse

slight better

a bit worse

much better

Question 5 of 10

Question 6 of 10

6. Cytologic maps can be considered to be of _____ resolution and hence somewhat ______ physical maps.

very low, inaccurate

very high, accurate

very low, accurate

very high, inaccurate

Question 6 of 10

Question 7 of 10

7. In medical applications, the ultimate goal of gene mapping is to disease genes.

False

True

Question 7 of 10

Question 8 of 10

8. Which of the following is incorrect about EULER?

It is an assembly algorithm

In this approach, a sequence fragment is broken down to tuples of five nucleotides

The tuples are distributed in a diagram with numerous nodes that are all interconnected

It uses a Eulerian Superpath approach, which is a polynomial algorithm

Question 8 of 10

Question 9 of 10

9. Genetic linkage maps, also called genetic maps, identify the relative positions of genetic markers on a chromosome and are based on how frequent the markers are inherited together.

True

False

Question 9 of 10

Question 10 of 10

10. Which of the following is untrue about cytologic maps?

They refer to banding patterns

They cannot be directly observed under microscope

They can be viewed on stained chromosomes

They can be directly observed under microscope

Question 10 of 10