Bioinformatics Mock Test 2

10%

Question 1 of 10

1. If the purpose is to calculate the probability of one event AND a second event, the odds scores for the events are _________

subtracted

added

multiplied and added

multiplied

Question 1 of 10

Question 2 of 10

2. Given a multiple alignment of three sequences, the sum of scores is calculated as the sum of the dissimilarity scores of every pair of sequences at each position.

True

False

Question 2 of 10

Question 3 of 10

3. The major disadvantage of the PRSS program is that it doesn’t allow partial shuffling.

True

False

Question 3 of 10

Question 4 of 10

4. As the amount of computational time and memory space required increases exponentially with the number of sequences, it makes the multidimensional search matrix method computationally prohibitive to use for a large data set.

False

True

Question 4 of 10

Question 5 of 10

5. Which of the following is incorrect regarding sequence homology?

Two sequences can homologous relationship even if have do not have common origin

It is an important concept in sequence analysis

When two sequences are descended from a common evolutionary origin, they are said to have a homologous relationship

When two sequences are descended from a common evolutionary origin, they are said to share homology

Question 5 of 10

Question 6 of 10

6. What is used to generate parameters for the extreme distribution?

The pool of alignment scores from the shuffled sequences

A single score of a shuffled sequence

The basic optimal score computed at the beginning of the test

The pool of alignment scores from the unshuffled sequences

Question 6 of 10

Question 7 of 10

7. If the selected window size is too long, sensitivity of the alignment is lost.

False

True

Question 7 of 10

Question 8 of 10

8. Which of the following is untrue about DCA?

If the sections are not short enough, further divisions are restricted as well

It works by breaking each of the sequences into two smaller sections

It stands for Divide-and-Conquer Alignment

The breaking points during the process are determined based on regional similarity of the sequences

Question 8 of 10

Question 9 of 10

9. A dotplot is a visual and qualitative technique whereas the sequence alignment is an exact and quantitative measure of similarity of alignments.

True

False

Question 9 of 10

Question 10 of 10

10. The first step in Genetic Algorithm is arranging the sequences to be aligned in rows.

True

False

Question 10 of 10