Bioinformatics Practice Test 3

1. In heuristic methods, speed doesn’t vary with the size of database.

False

True

2. Which of the following is untrue regarding the block analysis method?

Blocks represent a conserved region in the MSA

Blocks differ from profiles in lacking insert and delete positions in the sequences

Every column includes only matches and mismatches

Blocks may be made by searching for a section of an MSA alignment that is low conserved

3. The specificity refers to the ability to include incorrect hits.

True

False

4. Which of the following is not a variant of BLAST?

BLASTN

TBLASTNX

BLASTP

BLASTX

5. An increase in sensitivity is associated with _______ in selectivity.

no specific change

exponential increase

increase

decrease

6. The main feature of computer visualization programs is interactivity, which allows users to visually manipulate the structural images through a graphical user interface.

False

True

7. Dynamic programming method is the fastest and most practical method.

False

True

8. Which of the following is not correct about the stabilizing Forces?

Electrostatic interactions occur when excess negative charges in one region are neutralized by positive charges in another region

They include electrostatic interactions but not van der Waals forces, and hydrogen bonding

Electrostatic interactions are a significant stabilizing force in a protein structure

Protein structures from secondary to quaternary are maintained by noncovalent forces

9. FASTA and BLAST are __________ but __________ for larger datasets.

slower, less sensitive

slower, more sensitive

faster, less sensitive

faster, more sensitive

10. Par Align is a web-based server that uses parallel processors to perform exhaustive sequence comparisons using either a parallelized version of the Smith–Waterman algorithm or a heuristic program for further speed gains.

False

True