Bioinformatics Mock Test 6

10%

Question 1 of 10

1. The descriptions of morphological traits are often _____ which are due to _____

lucid, more than one genetic factors

ambiguous, one or two genetic factors

ambiguous, multiple genetic factors

clear, multiple genetic factors

Question 1 of 10

Question 2 of 10

2. Accurate prediction of _____ bonds may also help to predict the _____ dimensional structure of the protein of interest.

disulfide, three

nitrogen, three

nitrogen, two

oxygen, three

Question 2 of 10

Question 3 of 10

3. Which of the following is incorrect regarding the terminologies of phylogenetics?

In a monophyletic group, two taxa share a unique common ancestor shared by other taxa as well

A group of taxa descended from a single common ancestor is defined as a clade or monophyletic group

Lineage is often synonymous with a tree branch leading to a defined monophyletic group

When a number of taxa share more than one closest common ancestors, they do not fit the definition of a clade. In this case, they are referred to as paraphyletic

Question 3 of 10

Question 4 of 10

4. which of the following is incorrect about Oligonucleotide Design in A microarray?

DNA microarrays are generated by fixing oligonucleotides onto a solid support

The oligonucleotides don’t react with cDNA samples

The length of oligonucleotides is typically in the range of twenty-five to seventy bases long

The oligonucleotide array slide represents thousands of preselected genes from an organism

Question 4 of 10

Question 5 of 10

5. Which of the following is untrue about SAGE Genie?

It doesn’t filter out linker sequences from experimentally obtained SAGE tags

It allows matching of experimentally obtained SAGE tags to known genes

It is an NCBI web-based program

It provides an interface for visualizing human gene expression

Question 5 of 10

Question 6 of 10

6. Which of the following is untrue about SAGE?

Here, sequencing is economical but time-consuming step

It is difficult to know how many tags need to be sequenced to get a good coverage of the entire transcriptome

Sequencing is the most costly and time-consuming step

Sequencing is economical but time-reducing step

Question 6 of 10

Question 7 of 10

7. To minimize false-positive results, a statistical learning process called support vector machine (SVM) can be used to increase the specificity of prediction.

True

False

Question 7 of 10

Question 8 of 10

8. If the bait and prey proteins _______ they bring the DNA-binding and trans-activation domains in such close proximity that they reconstitute the function of the transcription activator, turning ____ the expression of a reporter gene as a result. Which of the following is not the correct pair of blanks?

do not interact, off

physically interact, on

stop interacting, off

do not interact, on

Question 8 of 10

Question 9 of 10

9. Which of the following is untrue regarding EST Index Construction?

The goal of the EST databases is to organize and consolidate the largely redundant EST data

The goal of the EST databases is to improve the quality of the sequence information so the data can be used to extract full-length cDNAs

The process includes a preprocessing step that removes masks repeats

There is no screening of vector contaminants

Question 9 of 10

Question 10 of 10

10. The signal sequences are typically _______ residues long, rich in _____ charged residues such as arginines as well as hydroxyl residues such as serines and threonines, but devoid of ______ charged residues.

300 to 500, positively, negatively

300 to 800, negatively, positively

28 to 80, negatively, positively

28 to 80, positively, negatively

Question 10 of 10

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