Drug and Pharmaceutical Biotechnology Practice Test 8

1. What are the characteristics of ion exchange resin drug complexes?

Hollow systems containing drug surrounded by a polymer membrane

Release the drug along the entire length of GIT

Drug disperse in an insoluble matrix of rigid hydrophobic materials

Formation of complexes between the drug and anion/cation exchange resins

2. What is gestational diabetes?

Immune cells destroy beta cells

The body becomes resistant to insulin

Increase of blood sugar

Occurs in a pregnant women

3. Clients with hypertension or HDL cholesterol < 35 mg/dL, and/or triglyceride level > 250 mg/dl may have diabetes.

False

True

4. Osmotic pressure controlled systems work on the principle of osmotic pressure releasing the drug at constant 1st order kinetics.

True

False

5. Which of the following oral controlled release system is shown in the picture?

Oral osmotic pump

Hydrodynamic pressure controlled system

Altered density systems

Reservoir device

6. Release of water-soluble drugs can be retarded by presenting it as ____________ suspension.

Freezing

Water

Oil

Colloidal

7. Which of the following is the definition for diabetes 1?

The immune system destroys beta cells and no more insulin is being produced

Insulin is produced but not efficiently used up

Receptors for insulin are destroyed

The body becomes resistant to insulin

8. Which of the following is a characteristic of nanoparticles?

Free flowing powders

Aqueous solutions

Control drug release by partitioning the drug from the oil

Size range 10-100 nm

9. Which one of the following is marketed by the name Levemir by Novo Nordisk?

Glargine

Insulin aspart

Glulisine

Detemir

10. Which of the following is a characteristic of aqueous solutions?

Administration of emulsions

Control drug release by partitioning the drug from the oil

Free flowing powders

Drug release can be increased by increasing viscosity