Drug and Pharmaceutical Biotechnology Mock Test 5

10%

Question 1 of 10

1. What is bioavailability?

The rate of absorption of the drug from its dosage form

The rate of absorption of the unchanged drug from its dosage form

The time of absorption of the drug from its dosage form

The time of absorption of the unchanged drug from its dosage form

Question 1 of 10

Question 2 of 10

2. What is bioequivalence?

Two or more drug products contain different labeled chemical substance giving the same therapeutic effect

Two or more drug products contain the same labeled chemical substance in different quantity

Two or more drug products contain the same labeled chemical substance giving a different therapeutic effect

Drug substance reaches the systemic circulation at the same rate in two or more identical dosage

Question 2 of 10

Question 3 of 10

3. Which of the following will not be a parameter that should be examined for urinary excretion data?

C_max

(dX_u/dt)_max

(t_u)_max

X_u

Question 3 of 10

Question 4 of 10

4. What does the specific receptor theory state?

Binding produces conformational changes

Produces chemical changes to the receptors

Tries to open all the closed sodium gates

Local anesthetics bind to various receptors

Question 4 of 10

Question 5 of 10

5. What is the principle behind the use of surfactants?

Reducing the size of solid drug particles

Improving solubility

Enhancing the dissolution rate by promoting wetting

Alter the pH of the microenvironment

Question 5 of 10

Question 6 of 10

6. Which of the following is the pharmacological action of local anesthetics?

Class II antidysrhythmic like action

Reversible block of conduction in nerve

Excitation of neuro-muscular transmission in skeletal muscle

Contraction of smooth muscle

Question 6 of 10

Question 7 of 10

7. Which of the following order of inducing cardiac arrhythmias of inhaled anesthetics is correct?

F > Cl > Br > I

Br < I < F < Cl

F < Cl < Br < I

F < Br < I < Cl

Question 7 of 10

Question 8 of 10

8. Which of the following are endogenous opioid peptides?

Oxycodone

Endomorphins

Fentanyl

Codeine

Question 8 of 10

Question 9 of 10

9. In vitro determination of bioavailability by dissolution rate is not the best way to determine therapeutic efficacy.

False

True

Question 9 of 10

Question 10 of 10

10. On which individuals study of newly invented medicines are not done?

Pregnant and elderly

Healthy person

Fasting person

Adult male

Question 10 of 10