Cytogenetics Mock Test 4

10%

Question 1 of 10

1. Which of the mutations can be detected Phenotypically?

Neutral

Reverse

Sense

Silent

Question 1 of 10

Question 2 of 10

2. Type I restriction endonuclease cuts________________

Within the recognition sequence

1000bp away from the recognition sequence

On either side of the recognition sequence

25 to 30 bp away from the recognition sequence

Question 2 of 10

Question 3 of 10

3. Which of this mutagen can lead to both AT->GC and GC->AT transition?

NH₂OH

Ethydium bromide

5 Bromo uracil

MMS

Question 3 of 10

Question 4 of 10

4. In EcoRV the enzyme is a ____________

Homo dimer

Hetero tetramer

Hetero dimer

Trimer

Question 4 of 10

Question 5 of 10

5. Which of the following is not a point mutation?

Insertion

Transversion

Transposition

Substitution

Question 5 of 10

Question 6 of 10

6. Which of the following is most flexible ligase?

ERCCI

Ligase I

Ligase X

Ligase IV

Question 6 of 10

Question 7 of 10

7. Which factor works in conjugation with FEN1?

PCNA

RPA

Pol beta

XRCC

Question 7 of 10

Question 8 of 10

8. Which of the following is not true about ATM kinase?

It is guided to the DSB site by MRN complex

It is activated to monomer by another factor of DSB repair

It phosphorylates BRCA1 and BRCA2

It exits as inactive dimer

Question 8 of 10

Question 9 of 10

9. Which of the following is not a function of APE1?

5’->3’ exonuclease

Generating abasic site

Improving fidelity of pol beta

Generating nick at 5’ end

Question 9 of 10

Question 10 of 10

10. In Ames test, the bacterial culture are grown in _________

Minimal media

Natural media

Enriched media

Blood agar

Question 10 of 10